Significant neuropsychiatric responses have actually happened in patients taking Zyban ® for smoking cigarettes cessation [view Warnings and Precautions (5.1)] The majority of these responses occurred during bupropion therapy, but some occurred in the context of ceasing treatment. In a lot of cases, a causal connection to bupropion treatment is not certain, considering that depressed state of mind may be a sign of pure nicotine withdrawal. Some of these symptoms have occurred in patients taking Zyban that proceeded to smoke.
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The threats of Zyban should be weighed versus the benefits of its use. Zyban has actually been shown to enhance the possibility of abstinence from cigarette smoking for as lengthy as 6 months contrasted regarding therapy regarding sugar pill. The health and wellness benefits of stopping smoking are prompt and considerable.
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Although Zyban is not shown for treatment of depression, it includes the same energetic substance as the antidepressant treatments WELLBUTRIN ®, WELLBUTRIN ® SR, and also WELLBUTRIN XL ®. Antidepressants increased the danger of self-destructive thoughts as well as behavior in youngsters, teens, as well as young people in short-term trials. These tests did disappoint an increase in the threat of suicidal thoughts and also behavior regarding antidepressant usage in topics over age 24; there was a reduction in risk with antidepressant usage in topics aged 65 as well as older [view Precautions and also warnings (5.
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